Alzheimer's

ENCORE: The Effects of Diet on Lifespan, Part 1
February 27, 2020
"The Longevity Diet," by Dr. Valter Longo, Director of the Longevity Institute at USC. The focus of his lifetime research has been to examine the effects of diet on lifespan. Drawing from molecular biology, the study of centenarians worldwide, and experimental research on animals and humans, he concludes that our modern diet and constant consumption have thwarted the body’s innate ability to regenerate itself at the cellular and organ levels. Caloric deprivation is part of our evolutionary heritage; our bodies are programmed to “reboot” in response to periods of nutritional insufficiency. But long-term caloric restriction (CR) has proven a mixed bag; it leaves some individuals frail and immuno-suppressed. As a healthier, more practical and more palatable alternative, he proposes a fasting mimicking diet (FMD), which restricts nutrient intake just enough for short intervals to switch on the body’s repair and rejuvenation capabilities. The FMD has demonstrated efficacy for weight loss, diabetes, cardiovascular disease, cancer, MS and Alzheimer’s; it may have broader applications to inflammatory and auto-immune disorders that are associated with aging. How often should the FMD be implemented? How does the Prolon program of FMD foods harness the benefits of periodic fasting without the risks associated with traditional fasts? What’s the ideal anti-aging diet for otherwise healthy adults? How can the FMD complement the benefits of standard cancer treatments? Why should protein-restriction be less rigorously applied to older individuals? Can time-restricted feeding (TRF) capture some of the benefits of fasting? Can TRF be taken too far? Click HERE for part 2.

Intelligent Medicine Radio Show for February 22, Part 2
February 24, 2020
Chile becomes a model for how governments can push back against industry purveyors of obesogenic foods and beverages; Supplements for diabetes/insulin resistance—but don’t forget diet! Major medical journal acknowledges Alzheimer’s is a sugar disease; Hearty breakfasts may be key to fat-burning, weight control; Study reveals majority of asymptomatic adults have abnormal knee MRIs; Popular antibacterial agent in toothpastes undermines bone density; Magnesium vs. cardiac arrhythmias. Click HERE for part 1. Click HERE for articles and resources relating to this podcast episode.

Intelligent Medicine Radio Show for February 1, Part 2
February 3, 2020
Does AHCC work for kids? Is there such a thing as an allergy to vitamin C? Pregnant women who consume artificial sweeteners give birth to heavier babies; We’re running out of antibiotics to treat ordinary strep throat; Resistance training is the key to healthy aging; Berberine vs. colon cancer; Cocoa’s performance-enhancing effects; Seniors who consume mushrooms suffer less cognitive decline. Click HERE for part 1. Click HERE for articles and resources relating to this podcast episode.

Intelligent Medicine Radio Show for January 25, Part 2
January 27, 2020
Acid blocker medications raise risk of allergies; How to wean off PPIs; What’s erysipelas? U.S. deaths from lead exposure 10 times higher than previously thought; IV vitamin C vs. sepsis; Can fish oil supplements make men sexier? Pomegranate juice forestalls memory loss in older adults; Sunshine can keep you svelte. Click HERE for part 1. Click HERE for articles and resources relating to this podcast episode.

ENCORE: Q&A with Leyla, Part 1
January 1, 2020
Nicotinamide Riboside shown to improve mitochondrial energy production and memory in Alzheimer's disease research. Great analysis of the canola oil/Alzheimer's study! Are there similar studies with other types of oil? A better version of vitamin B1 to help prevent Alzheimer's: Allithiamine. Click HERE for part 2.

ENCORE: Are mushrooms a “brain food”? Part 1
December 31, 2019
Dr. Robert Beelman, Professor Emeritus of Food Science and Director of the Penn State Center for Plant and Mushroom Products for Health, shares his latest research. A new study demonstrates that mushrooms are high in glutathione and ergothioneine, potent antioxidant compounds with anti-aging potential. In addition to these antioxidants, mushrooms are rich sources of fiber, vitamin D, as well as beta glucans, an important immune-enhancing polysaccharide. Dr. Beelman details research that suggests that consumption of ergothioneine confers protection against neurodegenerative diseases like Alzheimer’s, Parkinson’s Disease and multiple sclerosis. Daily consumption of a handful of commercial button mushrooms can deliver these benefits. Do cooking methods impact the delivery of healthy mushroom compounds? Do mushrooms deserve the reputation that they are grown in manure? How best to store mushrooms? Are Shitake, porcini, oyster and lion’s mane mushrooms even more potent sources of ergothioneine? What’s “Brain Boost Bread”? Click HERE for part 2.

ENCORE: Are mushrooms a “brain food”? Part 2

Dr. Hoffman continues his conversation with Dr. Robert Beelman, Professor Emeritus of Food Science and Director of the Penn State Center for Plant and Mushroom Products for Health. Click HERE for part 1.

ENCORE: Intelligent Medicine Radio Show for December 28, Part 1
December 30, 2019
Alzheimer’s rate to double in 20 years; Trans-fats hike risk of dementia—by 75%! Vitamin D confers protection against Alzheimer’s in new study; New “breakthrough” Alzheimer’s drug—is it likely to pan out? Landmark study validates targeted lifestyle interventions, supplements for dementia reversal; America’s fast-food chains get poor grades for antibiotic-laced fare. Click HERE for part 2. Click HERE for articles and resources relating to this podcast episode.

ENCORE: Intelligent Medicine Radio Show for December 28, Part 2

High-intensity interval training restores memory in seniors; Can alcohol trigger arthritis? Omega 3 consumption counteracts genetic susceptibility to obesity; Meshima mushroom demonstrates strong activity vs. breast cancer; Aged Garlic Extract shown to promote micro-circulation, may speed wound healing in diabetics; What is giant cell arteritis? Amazon lax on counterfeit supplements offered by shady 3rd party vendors; Proximity to fast food eateries tracks with kids’ obesity in NYC boroughs; Exposure to chemicals in plastic fosters children’s weight gain. Click HERE for part 1. Click HERE for articles and resources relating to this podcast episode.

Q&A with Leyla Christmas Edition, Part 2: Food Intolerances
December 25, 2019
My 5-year-old son has multiple food intolerances, asthma, eczema, and now bed-wetting. Help!; What do you think of the hCG diet? Would you advise it or do you think it's dangerous?; After Verticle Sleeve Gastrectomy, I've regained the weight! Would low carb dieting and intermittent fasting help me?; I'm APOE 4/4. Where do I go from here? Is Alzheimer's a certainty for me? Click HERE for part 1.