Aging

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Q&A with Leyla Christmas Edition, Part 2: Food Intolerances
December 25, 2019
My 5-year-old son has multiple food intolerances, asthma, eczema, and now bed-wetting. Help!; What do you think of the hCG diet? Would you advise it or do you think it's dangerous?; After Verticle Sleeve Gastrectomy, I've regained the weight! Would low carb dieting and intermittent fasting help me?; I'm APOE 4/4. Where do I go from here? Is Alzheimer's a certainty for me? Click HERE for part 1.



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ENCORE: Intelligent Medicine Radio Show for December 14, Part 2
December 16, 2019
Sugary beverages—even fruit juice and diet drinks—increase diabetes risk. A 71-year-old caller seeks answers for his progressive muscle loss; Teen diet may be key to prevention of Alzheimer’s Disease; High-dose vitamin D doesn’t prompt kidney stones, high blood calcium; Pistachios protect telomeres; Blueberries vs. metabolic syndrome; Bacopa for CFS; Want some plastic microparticles with that tea? Click HERE for part 1. Click HERE for articles and resources relating to this podcast episode.



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Q&A with Leyla, Part 2: Trials using ultrasound to treat Alzheimer’s disease?
December 11, 2019
I want to try citrus bergamot for my cholesterol. Are there any long-term harmful side effects?; Could you discuss Exosome therapy as a replacement and/or adjunct for stem cell therapy?; Are there any doctors in the MN area that treat leaky gut and histamine?; Do I have high or low stored copper? How can I assess if I have a deficiency or overload?; What do you think of the trials using ultrasound to treat Alzheimer's disease?; My friend had Shingles last July and while the rash has cleared, the pain is excruciating. Any recommendations? Click HERE for part 1.



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The Frontiers of Anti-Aging Research, Part 1
November 26, 2019
Frontiers of Anti-Aging research with Oliver Medvedik, Ph.D., Vice President of the Life Extension Research Foundation (LEAF). Is anti-aging research about targeting diseases that curtail lifespan, or does it seek to unravel the very mechanisms that drive aging itself? Is it possible to extend lifespan indefinitely? What might be the societal consequences of so many more old people? What are some of the leading current strategies for extending life? Where does exercise fit in? Diet? Brain fitness? Senolytic drugs? Stem cells? CRISPR? What sophisticated new tools are being employed to assess biological (as opposed to chronological) age? What is the “Agemeter”? What are some of the most formidable barriers to promoting universal longevity? What role for nicotinamide riboside? Telomere supplements? Intermittent fasting? Click HERE for part 2.



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The Frontiers of Anti-Aging Research, Part 2

Dr. Hoffman continues his conversation with Oliver Medvedik, Ph.D., Vice President of the Life Extension Research Foundation (LEAF). Click HERE for part 1.



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ENCORE: Intelligent Medicine Radio Show for November 23, Part 2
November 25, 2019
New test allows quick celiac diagnosis—without requiring lengthy gluten challenge; NSAIDS definitively linked to heart risk; For a modest fee, an Italian guide will help you experience the Neanderthal lifestyle; The MLB Paradox: Baseball players live longer! Supplements to prevent breast cancer recurrence; Should this X-ray make me worried? Electromagnetic fields curb aggressiveness of breast cancer; Electrical stimulation of ears may slow aging. Click HERE for part 1. Click HERE for articles and resources relating to this podcast episode.



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Leyla Weighs In: Dementia
November 22, 2019
Serum elaidic acid concentration and risk of dementia; The importance of Lutein.



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Q&A with Leyla, Part 2: Auto-Brewery Syndrome
November 20, 2019
Drunk man actually had auto-brewery syndrome; My orthopedist told me I will need a knee replacement soon. Would collagen supplements help?; My friend was diagnosed with a benign brain cyst. Could this be caused by a cell phone? Is surgery the only option?; Can you comment on the article, Rheumatoid Arthritis and "Night Shade Vegetables"?; I stopped taking thyroid replacement after hemithyroidectomy in 1980 because it wasn't well regulated. Now I have FMS. Click HERE for part 1.



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ENCORE: Reversal of Cognitive Decline, Part 1
November 19, 2019
Dr. Dale Bredesen is a board-certified neurologist who is author of a landmark paper entitled: “Reversal of cognitive decline: A novel therapeutic program.” He is founding president of the Buck Institute where world-class scientists tackle age-related problems. Dr. Bredesen is spear-heading research of a comprehensive program for reversing symptoms of dementia with lifestyle modification, supplements, diet, bio-identical hormones, and detoxification. A huge problem looms as millions of aging Baby Boomers become candidates for Alzheimer’s: for those without the ApoE4 allele, the risk is 9%; with one of two alleles, it soars to 30%; and with a “double-hit” of ApoE4 the risk becomes 90%. Dr. Bredesen is critical of the current “magic bullet” approach to development of Alzheimer’s drugs. While not discounting their potential, he believes the problem is so multi-faceted that it will require attention to numerous modifiable risk factors. “Normal” levels of B12, homocysteine, vitamin D, insulin, and C-reactive protein may not be optimal for prevention of cognitive decline. Adequate sleep, stress reduction, and exercise are lifestyle approaches that need to be deployed aggressively to counter memory loss. Promising supplements include resveratrol, DHA, Lion’s Mane, Bacopa, Ashwaganda, acetyl-l-carnitine, curcumin, citicholine, and nicotinamide riboside. Attention must be given to hormones, especially testosterone and pregnenolone which can be neuro-protective. Heavy metals like iron, mercury, lead and cadmium are implicated in some cases of cognitive decline. When it comes to diet, some controversy remains, but the ideal food program should target insulin resistance and inflammation. To this end, ketogenic diets, plant-based nutrition, gluten-avoidance and intermittent fasting show promise. Dr. Bredesen has demonstrated that cognitive decline CAN be reversed with a multi-factorial approach; if inaugurated early enough, patients can experience dramatic recovery of functionality. Click HERE for part 2.



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ENCORE: Reversal of Cognitive Decline, Part 2

Dr. Hoffman continues his conversation with Dr. Dale Bredesen, board-certified neurologist who is author of a landmark paper entitled: “Reversal of cognitive decline: A novel therapeutic program.” Click HERE for part 1.



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