Microbiome

Harnessing Human Milk Biology, Part 1
June 19, 2024
Alex Martinez, CEO and co-founder of Intrinsic Medicine reveals the potential of utilizing human milk biology, specifically the microbiome and human milk oligosaccharides (HMOs), to address various medical challenges such as Parkinson's disease, autism spectrum disorder, irritable bowel syndrome, Alzheimer's disease, and inflammatory bowel disease. Alex shares his journey from being an attorney to starting a therapeutics company focused on the innovative use of human milk's properties. The conversation also delves into the science behind HMOs, their evolutionary significance, and their potential impact on the microbiome and immune system. This episode provides insights into the cutting-edge research and the promising future of natural, less toxic, and cost-effective therapeutic solutions. Click HERE for part 2.

Harnessing Human Milk Biology, Part 2

Dr. Hoffman continues his conversation with Alex Martinez, the CEO and co-founder of Intrinsic Medicine, a therapeutics company leveraging human milk biology to transform Gut-Immune-Brain Axis (GIBA) disorders such as Parkinson’s, Autism Spectrum Disorder, IBS, Alzheimer’s, and IBD, among other illnesses. Click HERE for part 1.

Leyla Weighs In: Unveiling the Microbiome Theory of Aging (Second in a Series)
June 7, 2024
Nutritionist Leyla Muedin delves into the Microbiome Theory of Aging as outlined in Dr. Ross Pelton's article from the Integrative Medicine Clinician's Journal. The series explores the connection between gut health, dysbiosis, and aging, highlighting the role of dietary fibers and polyphenols in feeding probiotic bacteria to produce beneficial postbiotic metabolites. It also discusses zonulin's role in intestinal permeability, the negative impacts of the standard American diet on microbiome health, and the importance of a diverse plant-based diet for nurturing a healthy microbiome. Additionally, the episode critiques the efficacy of commercial probiotics versus the benefits of postbiotics and introduces postbiotic metabolites as an emerging, effective approach to improving gut health and overall wellness.

Leyla Weighs In: Unveiling the Microbiome Theory of Aging (First in a Series)
May 31, 2024
Nutritionist Leyla Muedin details the Microbiome Theory of Aging (MTA) through a comprehensive article by Ross Pelton in Integrative Medicine, a Clinician's Journal. The theory suggests that dysbiosis, or microbial imbalance in the gut, causes health problems that can accelerate biological aging by increasing inflammation, zonulin levels, intestinal permeability (leaky gut), and triggering chronic diseases. The episode covers the roles of probiotics, postbiotics, and how lifestyle factors influence the aging process. Leyla also discusses causes of dysbiosis, including diet, antibiotics, and stress, and introduces the concept of postbiotic metabolites as key regulators of health. The importance of the gut-brain axis and the effect of stress on microbiome dysfunction are also highlighted. The talk aims to provide insight into how maintaining a healthy gut microbiome can influence aging and health, setting the stage for a deeper dive in the next episode.

Postbiotic Metabolites: The New Frontier in Microbiome Science, Part 1
May 28, 2024
Dr. Ross Pelton, a renowned expert on the microbiome and Director of Science and Education for Essential Formulas, Inc. discusses the 'oral probiotic dilemma,' highlighting the challenges and misconceptions about probiotics, the importance of dietary fibers and polyphenols, and the role of postbiotic metabolites in health. He details scientific studies demonstrating the benefits of optimizing the gut microbiome and explores Dr. Ohhira's Probiotics and their unique fermentation process. The episode also touches on the broader health impacts of a healthy gut microbiome, including its potential in anti-aging and overall wellness. Click HERE for part 2.

Exploring the Critical Link Between Gut Health and Overall Wellbeing with Dr. Michael Ruscio, Part 1
April 9, 2024
Have you ever considered that the key to your mood swings or unshakeable fatigue might be lurking within your gut? This episode pulls back the curtain on our digestive systems with the expertise of Dr. Michael Ruscio, gut health guru and author of "Healthy Gut, Healthy You." We embark on an eye-opening discussion about the often underestimated power of the gastrointestinal tract, from its influence on our energy and sleep to its intricate connection with mental health and thyroid function. Dr. Ruscio shares his own transformative experience, revealing how a gut infection could disguise itself as insomnia and emotional turbulence. As we unravel the threads between what we eat, how we feel, and the health of our gut, the conversation turns to the interplay between diet and chronic conditions like Hashimoto's disease. Dr. Ruscio offers invaluable insights into the nuances of dietary interventions such as the low FODMAP and autoimmune paleo diets, urging a thoughtful approach to food choices that transcends the fads and fears of unnecessary restrictions. We dissect the hype around gluten-free living, providing a balanced perspective on when it's truly integral to our health and when it might be overkill. If you've ever felt overwhelmed by conflicting dietary advice, this discussion aims to bring clarity and empower your decision-making. Closing out this enlightening journey, we dive into the promise of probiotics and botanicals, exploring the intersection of gut flora, metabolic health, and the use of 'triple therapy' probiotics. However, it's not just about what you ingest – we also delve into the pivotal role of mental wellness in physical health. I share strategies that fortify mental resilience, such as limbic retraining and embracing nature. Dr. Ruscio brings it all together, providing a roadmap for navigating the complex synergy of our minds, immune systems, and gut health. Tune in and equip yourself with the knowledge to steer your health towards a more harmonious future. Click HERE for part 2.

Exploring the Critical Link Between Gut Health and Overall Wellbeing with Dr. Michael Ruscio, Part 2

Dr. Hoffman continues his conversation with Dr. Michael Ruscio, author of “Healthy Gut Healthy You.” Click HERE for part 1.

ENCORE: Connecting the Dots Between Your Gut Health and Many Common Ailments, Part 1
January 4, 2024
Dr. William Davis, author of the best-selling Wheat Belly series, focuses on the microbiome in his new book "Super Gut: Reprogram Your Microbiome to Restore Health, Lose Weight, and Turn Back the Clock." Dr. Davis relates how the limitations of his conventional cardiology training led him to explore natural alternatives, which fundamentally altered his patients’ trajectory to heart disease. He describes the rationale for gluten avoidance as a path, not just to weight loss, but also to overall health restoration. Dr. Davis goes beyond mere gluten avoidance; it’s necessary to curtail many other offending grains and embrace a low-carb diet. His research has revealed that homemade yogurts, made with specific starters, have a wide range of benefits. A polyphenol and prebiotic-rich diet, probiotic replacement, as well as certain nutraceuticals are critical to restoration of gut integrity. Click HERE for part 2.

ENCORE: Connecting the Dots Between Your Gut Health and Many Common Ailments, Part 2

Dr. Hoffman continues his conversation with Dr. William Davis, author of "Super Gut: Reprogram Your Microbiome to Restore Health, Lose Weight, and Turn Back the Clock." Click HERE for part 1.

Immune Essentials with Dr. Ross Pelton, Part 1
November 2, 2023
Fall is here and winter is coming. This is the time of year we want to emphasize the importance of a strong immune system. And with 70% of your body’s immune cells residing in the gut, healthy digestion is a good foundation to good immune response. Dr. Ross Pelton, pharmacist, clinical nutritionist, health educator, author of twelve books, and Director of Science & Education for Essential Formulas Incorporated, details KEY nutritional supplements that are recognized to help enhance immune health during the colder weather, including the postbiotic metabolites that are included in Dr. Ohhira's Probiotics. Click HERE for part 2.