Expert Interview

Breathing Easier: Natural Solutions for Seasonal Allergies with Nate Jones, Part 2
May 21, 2024
Dr. Hoffman continues his conversation with Nathan Jones, CEO and Founder of Xlear, Inc. Click HERE for part 1.

Feeding the Brain: Nutrients for Memory, Focus, and Aging, Part 1
May 15, 2024
Neil Levin, a clinical nutritionist and expert formulator for Protocol for Life Balance details nutritional support for brain health. He covers the rising burden of Alzheimer's and cognitive decline, emphasizing the importance of lifestyle factors such as diet, sleep, and exercise in supporting brain function. Levin shares insights on how changes in the brain, including the development of plaques and tangles, free radical damage, and inflammation, affect aging and cognitive health. He reveals nutritional approaches to address these issues, including the roles of magnesium, omega-3 fatty acids, and specific nutrients like curcumin and GABA in supporting brain health. The podcast episode also delves into the benefits of certain supplements like Magtein (magnesium L-threonate) and Cogumin SLCP (a form of curcumin), discussing their efficacy in crossing the blood-brain barrier and supporting cognitive function. Click HERE for part 2.

Feeding the Brain: Nutrients for Memory, Focus, and Aging, Part 2

Dr. Hoffman continues his conversation with Neil Levin, the Senior Nutrition Education Manager and a product formulator for NOW(r) Foods and Protocol for Life Balance. Click HERE for part 1.

Turning the Tide on Overmedication: Dr. Mark Horowitz’s Approach to Deprescribing, Part 1
May 14, 2024
Dr. Mark Horowitz, a Clinical Research Fellow in Psychiatry from the UK and co-author of “The Maudsley Deprescribing Guidelines: Antidepressants, Benzodiazepines, Gabapentinoids and Z-drugs,” delves into the complexities of deprescribing psychiatric medications such as antidepressants, benzodiazepines, and sleep aids. Dr. Horowitz outlines the origins and importance of the deprescribing movement, explaining how polypharmacy and overprescription have necessitated a careful approach to reducing medication loads safely. He discusses the physiological and withdrawal challenges faced by patients on long-term psychiatric medication, emphasizing the vital role of slow and individualized tapering processes. He covers the substantial influence of pharmaceutical companies on prescription guidelines in the US compared to the UK, shedding light on the differences in medication usage and prescribing cultures. Dr. Horowitz also debunks the chemical imbalance theory of depression, arguing for a more nuanced understanding of mental health issues and their treatment. He introduces Outro, a new clinic founded by Dr. Horowitz in California, aimed at supporting individuals through the deprescribing process. Click HERE for part 2.

Turning the Tide on Overmedication: Dr. Mark Horowitz’s Approach to Deprescribing, Part 2

Dr. Hoffman continues his conversation with Dr. Mark Horowitz, co-author of "The Maudsley Deprescribing Guidelines: Antidepressants, Benzodiazepines, Gabapentinoids and Z-drugs." Click HERE for part 1.

ENCORE: Factors That Affect Fertility, Part 1
May 8, 2024
Infertility is an increasing problem. Many couples are facing challenges, but few realize that men are an important part of the fertility equation. Sperm quality is recognized to be declining worldwide. Ayla Barmmer, a Registered Dietician and functional medicine practitioner is the founder and CEO of FullWell, a fertility wellness and education brand. She discusses lifestyle factors that affect fertility: exercise, diet, weight optimization, stress, and sleep. Additionally, environmental toxicity can take a toll on sperm and egg viability. A few specific nutrients are essential for fertility optimization, which she enumerates. Not only can barriers to pregnancy be surmounted, but proper pre-conceptual planning can optimize the physical and mental health of offspring—even with lasting trans-generational effects for descendants. Click HERE for part 2.

ENCORE: Factors That Affect Fertility, Part 2

Dr. Hoffman continues his conversation with Ayla Barmmer, a Registered Dietician and functional medicine practitioner, and founder and CEO of FullWell, a fertility wellness and education brand. Click HERE for part 1.

ENCORE: A New Revolutionary Technology That Can Predict Cardiovascular Risk With Precision, Part 1
May 7, 2024
Current ways of visualizing the coronary arteries with calcium scoring are limited: the presence of calcium doesn’t always determine risk; its absence doesn’t fully eliminate the possibility of soft plaque, which is actually more dangerous than stable calcium deposits. Dr. James Min is an expert on cardiovascular imaging and founder and CEO of Cleerly, a company that has developed an improved scan that can differentiate between dangerous unstable plaque, and more benign lesions. The test can be used to establish risk, and then medication and/or lifestyle modification with diet, stress reduction, exercise and supplements can be undertaken. Subsequent tests can yield a report card for how successful the preventive interventions have been. Dr. Min emphasizes that even in settings of high cholesterol the test can show minimal risk, reducing the need for cholesterol medication; conversely, people with low cholesterol may have substantial dangerous plaque. The Cleerly test promises to revolutionize our approach to cardiovascular prevention. Click HERE for part 2.

ENCORE: A New Revolutionary Technology That Can Predict Cardiovascular Risk With Precision, Part 2

Dr. Hoffman continues his conversation with Dr. James Min, an expert on cardiovascular imaging and founder and CEO of Cleerly, a company that has developed an improved scan that can differentiate between dangerous unstable plaque, and more benign lesions. Click HERE for part 1.

ENCORE: A Novel, Newly-Discovered Nutraceutical, Part 1
May 1, 2024
The Annatto plant is valued as a rich source of tocotrienols and a novel, newly-discovered nutraceutical: geranylgeraniol (GG). Dr. Barrie Tan, a Ph.D. biochemist who discovered GG, and Dr. David Brady, former director of the Human Nutrition Institute at the University of Bridgeport and author of numerous books and scientific papers, join us to discuss the roles of tocotrienols and GG in human health. Traditional forms of vitamin E supplements—the tocopherols—are being superseded by tocotrienols as more therapeutic forms of vitamin E. Tocotrienols have shown promise in oncology, for supporting liver health, and for protecting cell membranes as potent fat-soluble antioxidants. GG is ubiquitous as a precursor of diverse compounds including CoQ10, active vitamin K, sex steroids, and proteins. It is useful as a general preventive supplement as well as for specific applications like offsetting CoQ10 depletion in statin users, in metabolic syndrome, and for staving off sarcopenia. Drs. Brady and Tan share their experience in dosing Annatto products, which come in a variety of iterations, alone or teamed with other supplements. Click HERE for part 2.