Intelligent Medicine®

From Mitochondria to Metabolism: Understanding Your Energy Allocation

Download as PDFPrint

Dr. Corey Schuler, PhD(c), FNP, DC, CNS, and director of medical affairs at Allergy Research Group, details his paper “Energy Allocation Resilience and Endocrine Integration” in the International Journal of Molecular Sciences. He introduces the Energy Allocation System (EAS), which emphasizes how the body allocates energy—not just produces it—and links many symptoms to impaired bioenergetics and resilience. They discuss mitochondria as energy generators and cellular signaling hubs, the integrated stress response and endocrine coordination (HPA axis, thyroid, gonads), and mitohormesis/eustress (exercise, fasting, heat/cold, circadian “zeitgebers”). Schuler explains nuanced testing for fatigue (diurnal cortisol, CGM patterns, thyroid markers including T3/reverse T3) and a case of a perimenopausal woman where oral contraceptives and cortisol dysregulation affected glucose patterns. They cover mitochondrial support (removing obstacles like pollutants/antibiotics, triglycerides, carnitine, dietary fats, micronutrients) and pacing/sequencing lifestyle interventions.

You may also like...

Featured Article
Latest Podcast
Featured Product

The science of you, working better.

There’s a crucial molecule in your body that helps control your circulation, your energy, your stamina, your heart—even your sharpness of mind. It’s called nitric oxide.

After age 40, your body makes less and less of it. That means less blood flow. Less stamina. Less of you. But now there’s N1O1 nitric oxide lozenges, developed by Dr. Nathan Bryan — the world’s leading nitric oxide researcher.

I take them twice a day, especially before my workouts, to support healthy circulation and boost oxygen delivery to my muscles and brain. 

N1O1 is designed to naturally restore your body’s nitric oxide levels, and goes to work in minutes, releasing nitric oxide directly into your bloodstream, and helping you feel the way you’re supposed to feel.

More energy. Better blood flow. Sharper focus. Day after day.

Use coupon code HOFFMAN10 to save 10%.

Learn more…