Intelligent Medicine®

GLP-1 Support Protocol

A 3d rendering of pre-filled GLP-1 receptor agonist pens, used for the treatment of type 2 diabetes or for weight management. It's disposable or multi-dose reusable pen.

They’re the Holy Grail of BigPharma—weight loss drugs that really work. For my entire professional career, drug developers have been on a quest to develop drugs that peel away the pounds, only to founder. Then, in a now-legendary discovery, scientists harnessed the chemical messenger that enabled Gila monsters to withstand long periods of caloric deprivation—and voila!—a generation of revolutionary weight loss drugs was spawned. 

It’s estimated that 12% of American adults have tried weight loss drugs; 6% of them continue to take them. If you fall into that group, my new GLP-1 Support Protocol can help support your nutritional needs while taking these medications.

Core Supplements

Protein: People on diet drugs need to prioritize protein sources and consider adding supplemental protein in the form of healthy shakes.

Aim for at least 0.8 grams of protein per pound of ideal body weight (see IBW calculator here). For example, I’m 5’10, and even if I weighed 220, my ideal body weight is 165, thus requiring around 130 grams of protein to stave off fat loss in the face of severe caloric restriction. 

I would especially add creatine monohydrate because of its potential for fending off muscle wasting. (5-10 grams per day.)

Because of limited food intake, it’s important to consider a multi-vitamin/mineral as nutritional insurance. I recommend Alpha Base from Ortho Molecular. (Take one, twice daily.)

Eating less means fewer opportunities to obtain essential fatty acids; my choice these days is Omega-3 Rejuvenate from Big Bold Health. (Take two, once daily.)

Diet restriction may cause unfavorable alterations in the microbiome, compounding the GI side effects of weight loss drugs. Hence, I recommend a probiotic (which also delivers pre- and post-biotics), Dr. Ohhira’s Essential Formula. (Take one, twice daily.)

To address off-ramping from GLP-1 medications, when rebound weight gain looms, I recommend Calocurb, a concentrate of New Zealand hops. I’m impressed with the rigor of their research, which shows this bitter extract stimulates endogenous production of satiety hormones.

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*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.

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