Dr. David Perlmutter

ENCORE: A Pandemic of Elevated Uric Acid, Part 1
February 1, 2024
Dr. David Perlmutter, integrative neurologist and author of "Grain Brain," has a new book: "Drop Acid: The Surprising New Science of Uric Acid—The Key to Losing Weight, Controlling Blood Sugar, and Achieving Extraordinary Health." Dr. Perlmutter highlights the central role that uric acid plays in, not just gout, but a plethora of metabolic and degenerate conditions that afflict modern men and women. He decries the lax guidelines that allow at-risk patients to suffer high uric acid, and argues for more stringent standards, preferring a uric acid of 5.5 or less as optimal. He describes how uric acid was once adaptive in prehistoric times as a measure to offset times of famine; now, with sedentary lifestyles, unlimited food, and vastly increased carbohydrate consumption, there’s a pandemic of elevated uric acid. He dispels the notion that lowering uric acid is just a matter of avoiding animal protein; dietary fructose from soft drinks and processed food and desserts is a far worse culprit. Dr. Perlmutter highlights certain nutrients that lower uric acid: vitamin C, coffee polyphenols, tart cherry concentrate, luteolin, and quercetin. What type of alcohol we consume also has an impact on uric acid, as does excessive salt consumption. Dr. Perlmutter introduces us to a home test that can empower patients to monitor their uric acid. Click HERE for part 2.

ENCORE: A Pandemic of Elevated Uric Acid, Part 2

Dr. Hoffman continues his conversation with Dr. David Perlmutter, integrative neurologist and author of the new book, "Drop Acid: The Surprising New Science of Uric Acid—The Key to Losing Weight, Controlling Blood Sugar, and Achieving Extraordinary Health." Click HERE for part 1.

ENCORE: The Epidemic of Diabetes, Part 1
November 3, 2020
Dr. David Perlmutter is America’s foremost Integrative neurologist and pioneering author of "Grain Brain." Five years after its publication, with over a million copies sold worldwide in twenty languages, he reflects on its success and the vindication of its central tenets: That America’s low-fat high/carb mania has promoted an epidemic of diabetes, just when optimal blood sugar is gaining recognition as fundamental to brain health; that gluten is demonstrably harmful via its effects on gut permeability; and that fat and cholesterol phobia has deprived our brains of essential nutrients. He emphasizes the centrality of exercise to prevention and reversal of dementia. The latest research underlies the concept of neuroplasticity—that the adult brain has the capacity to repair and regenerate. What newly-discovered factor helps to literally regrow brain cells? Does genetics dictate our neurological fate? Or can lifestyle overcome our heredity? What roles for sleep? Stress reduction? Coffee? Alcohol? Bio-identical hormone replacement? The microbiome? Cannabinoids? Ketogenic diet? What drugs take a toll on brain function? Dr. Perlmutter will soon be featured nationwide in a PBS Special entitled “Dr. Perlmutter’s Whole Life Plan”. Click HERE for part 2.

ENCORE: The Epidemic of Diabetes, Part 2

Dr. Hoffman continues his conversation with Dr. David Perlmutter, America’s foremost Integrative neurologist and pioneering author of "Grain Brain." Click HERE for part 1.

How Modern Culture Rewires our Brains and Damages our Health, Part 1
September 26, 2019
Dr. David Perlmutter, “The Empowering Neurologist,” rolls out some new projects: "Alzheimer’s—the Science of Prevention," a webinar due out October ‘19; "The Microbiome and the Brain" in December; and the new book "Brain Wash: Detox Your Mind for Clearer Thinking, Deeper Relationships, and Lasting Happiness," available in January 2020 - preorder now. Is Dr. Perlmutter still persuaded about the perils of gluten, as previously outlined in "Grain Brain?" What’s more harmful to the brain—excess carbs or saturated fat and cholesterol? Can the ApoE4 gene be overcome with diet and lifestyle measures? What supplements does Dr. Perlmutter recommend for neuroprotection? What about CBD? Why does he claim we are literally and figuratively being “brainwashed”? What roles for exercise, sleep, exposure to nature, fasting, Keto diet, caloric restriction, metformin? Click HERE for part 2.

How Modern Culture Rewires our Brains and Damages our Health, Part 2

Dr. Hoffman continues his enlightening conversation with Dr. David Perlmutter, “The Empowering Neurologist." Click HERE for part 1.

ENCORE: The Grain Brain Cookbook, Part 1
November 24, 2016
Integrative neurologist Dr. David Perlmutter discusses his new book, The Grain Brain Cookbook. Why is a low-carb, ketogenic diet beneficial for the brain? How does gluten wreak havoc on the nervous system? What results are Dr. Perlmutter seeing in treatment of patients with Alzheimer's Disease, Parkinson's, MS, and ALS? Click HERE for part 2.

ENCORE: The Grain Brain Cookbook, Part 2

Dr. Hoffman continues his conversation with Dr. David Perlmutter about his new book, The Grain Brain Cookbook. Click HERE for part 1.

Gut Microbes and the Brain, Part 1
April 28, 2015
Dr. David Perlmutter, America's foremost integrative neurologist, author of the best-seller "Grain Brain," joins us to discuss his new book "Brain Maker: The Power of Gut Microbes to Heal and Protect Your Brain for Life." What's our new understanding of the relationship between the gut and the brain? What do experiments with fecal microbiota transplantation (FMT) suggest as a novel means of curing neurological disorders--from MS to autism to Alzheimers. Does "leaky gut syndrome" play a role in brain inflammation? Is a gluten-free, ultra low-carb diet the solution for everyone? Can probiotics and fermented foods enhance mood? What key supplements support brain and gut health? Click HERE for part 2.

Gut Microbes and the Brain, Part 2

Dr. Hoffman continues his conversation with Dr. David Perlmutter about our new understanding of the relationship between the gut and the brain. Click HERE for part 1.