Top Ten Intelligent Medicine Podcasts of 2025

‘Tis the season! As the pace of work and school slows, and the freneticism of shopping and parties abates, people are hopping into cars, buses, planes and trains to reach holiday destinations. Or else, they collapse and simply enjoy cocooning at home with family.

It’s a perfect time to relax while catching up on some of our best Intelligent Medicine podcast episodes of 2025 that you may have missed (we’ve generated over 200 shows with timely, original, free content this year alone!). To date there have been over 13 million downloads since we launched our popular podcast series!

While all of our Intelligent Medicine podcast episodes have been great this year, here are ten I’d like to especially highlight:

1) The Revolutionary Role of the Vagus Nerve in Bioelectronic MedicineWith Dr. Kevin J. Tracey, president and CEO at the Feinstein Institutes for Medical Research, author of “The Great Nerve: The New Science of the Vagus Nerve and How to Harness Its Healing Reflexes.” Dr. Tracey details the historical context and recent advancements in harnessing the power of the vagus nerve to control inflammation. He explores the journey from early experimental stages to the recent FDA approval for treating rheumatoid arthritis through vagus nerve stimulation (VNS) devices. He also delves into the potential applications of VNS in treating other inflammatory conditions, mood disorders, and the science behind non-invasive lifestyle techniques and commercially available devices. The episode provides valuable insights into the future of bioelectronic medicine and its potential to revolutionize medical treatments.

2) Deep-seated corruption in Alzheimer’s research: Investigative journalist Charles Piller blows the whistle on corruption in Alzheimer’s research in his book, “Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s Disease.” We delve into the issues surrounding Big Pharma’s influence, fraudulent scientific studies, and the implications of a controversial 2006 experiment at the University of Minnesota. He critiques costly and marginally effective Alzheimer’s drugs like Aducanumab, and highlights the challenges faced by alternative research hypotheses, and the significance of improving scientific integrity and checks and balances in medical research.

3) Dr. Jeffrey Bland, pioneer in the field of integrative and functional medicine: Dr. Bland  discusses his latest project, Big Bold Health, which focuses on immune system rejuvenation through natural products like HTB (Himalayan Tartary Buckwheat) and high-quality fish oil. Our conversation delves into the origins and benefits of functional medicine, the importance of diet and lifestyle in health, and the concept of making America healthy. Dr. Bland also shares insights into his journey and the influence of natural medicine practices. Listeners are encouraged to explore more about functional medicine and Big Bold Health’s unique offerings.

4) Integrative Rheumatology with Dr. Aly Cohen: Dr. Cohen, a board-certified rheumatologist and integrative medicine physician talks about the pervasive issue of environmental toxins and their adverse effects on health. Dr. Cohen, who also manages the environmental medicine curriculum at the University of California, Irvine, discusses insights from her new book “Detoxify: The Everyday Toxins Harming Your Immune System and How to Defend Against Them.” The conversation covers practical steps to mitigate exposure to harmful chemicals, the rise of autoimmune diseases, and strategies for detoxification, including diet, exercise, and proper hydration. Dr. Cohen also shares her personal journey into environmental health, sparked by her dog’s illness, and emphasizes the importance of proactive self-care in a world filled with toxins.

5) Health Freedom on Trial: Constitutional attorney Jonathan Emord discusses his extensive career advocating for health freedom, focusing on natural health products and constitutional law. Emord explains the legal battles and regulatory challenges faced by the natural health industry, particularly against FDA and FTC overreach. He highlights victories like the overturning of the Chevron doctrine, a longstanding rule that saw courts deferring to independent agencies on some cases, as well as recent successes in court that have implications for the natural products industry. The conversation also covers the harmful impact of the COVID-19 pandemic on health freedom, and the ongoing efforts to secure access to truthful health information for consumers.







6) The Healing Science of Mitochondria: Dr. Martin Picard, Chair in Energy and Health, and Professor of Behavioral Medicine at Columbia University, as well as head of the Mitochondrial PsychoBiology Lab, delves into the complex functions of mitochondria beyond their well-known role as cellular powerhouses. Dr. Picard shares his journey from biology to psychobiology, exploring the intersection between mitochondrial function, mental health, and overall well-being. He discusses how mitochondria not only produce energy but also influence behaviors, stress responses, and healing processes. The conversation highlights recent findings on mitochondrial roles in psychiatric disorders, the impact of diet and lifestyle on mitochondrial health, and the potential of ketogenic diets in treating psychiatric conditions. Dr. Picard also previews his upcoming book on understanding life and health from an energetic perspective. The episode emphasizes a holistic approach to health, integrating mind-body practices and lifestyle changes to support mitochondrial function.

7) Satiety Matters When it Comes to Weight Loss: Dr. Andreas Eenfeldt, a Swedish family medicine physician and CEO of Diet Doctor, discusses the evolution of dietary assessment paradigms, from calorie counting to the glycemic index, and introduces the concept of satiety in modern diet planning. Dr. Eenfeldt introduces HAVA, a new app designed to simplify diet tracking using an innovative algorithm that scores foods based on four key factors: protein content, energy density, fiber, and hedonic value. The app utilizes AI technology for food identification and personalized guidance, making it user-friendly and highly effective for weight management and metabolic health. Highlighting the detrimental role of ultra-processed foods in weight gain, Dr. Eenfeldt explains how higher satiety foods can naturally help reduce calorie intake without hunger. The conversation also touches on the viability of various diets, including the carnivore and Nordic diets, and the complementary role of GLP-1 drugs.

8) The Protein Paradigm: Redefining Dietary Guidelines: Dr. Nina Teicholz, a PhD nutritionist, founder of the Nutrition Coalition, and author of “The Big Fat Surprise“ discusses the controversies around dietary guidelines, particularly the misrepresentation of low-fat diets and the critical role of protein in optimal health. Dr. Teicholz addresses the flaws in the U.S. Dietary Guidelines, highlights the impact of institutionalized groupthink on nutrition science, and argues for the reassessment of protein recommendations and the demonization of saturated fats. She also examines the challenges and influence of food industry conflicts on public health policies and shares insights on the potential for meaningful reform under the current administration.

9) Urolithin A: Dr. Brad Currier, Clinical Trial Manager at Timeline delves into the complexities of mitochondrial health. The podcast covers the critical role mitochondria play in cellular energy, gene expression, hormone synthesis, and insulin sensitivity. Dr. Currier discusses the development and benefits of Mitopure, a product based on Urolithin A, a compound shown to enhance mitochondrial function and health span. Topics include recent clinical studies demonstrating improved physical performance and recovery, the unique properties of Urolithin A, and how it supports cellular processes like mitophagy and immune response. The episode emphasizes the importance of mitochondrial efficiency for overall well-being and features an in-depth look at the scientific research behind Mitopure.

10) Water Quality and Filtration:  Cydian Kauffman, CEO of Pure Water Northwest, delves into the intricacies of water quality and filtration. Kauffman, an expert in making water quality understandable and accessible, discusses the various methods to test and improve water quality, the efficacy of different water filtration systems, and common misconceptions about water contaminants. We explore the advantages and limitations of carbon filters and reverse osmosis systems, address concerns about municipal water safety, and consider the presence of microplastics and forever chemicals in tap water. She provides practical advice for consumers on selecting appropriate filtration systems and understanding the importance of regular water testing. We explore broader water quality issues, including potential health impacts of novel pollutants and the geopolitical impact of water scarcity.

Enjoy these and other podcasts in our vast audio library and archive, and take advantage of your opportunity to pose questions or share comments via questions@drhoffman.net or 877-726-8255.

Best wishes for a safe, healthy, prosperous and fulfilling holiday season for you and your loved ones