Q&A with Leyla, Part 1: Reasons for Nausea

• Reasons for nausea  
• My PSA was 4.0 six months ago, and now it’s up to 4.55. What should I do?
• I have lupus and need to take Methotrexate. How can I protect my liver and immune system?
• The important relationship between vitamin D3 and K2

Q&A with Leyla, Part 2: Can Fish Oil Raise LDL Cholesterol?

• How do I keep my LDL low enough without compromising my brain and my liver?
• I read that fish oil can raise LDL cholesterol. Is this true?
• A questionable case study on pycnogenol

Dr. Geo Espinosa, one of America’s foremost integrative urologists, dishes on men’s urinary problems, natural support for testosterone, and prostate cancer. Lifestyle factors—diet, exercise, sleep and stress reduction—play an important role in all phases of urological health. Dr. Geo explains how he interacts with conventional urologists on the faculty of NYU Langone Medical Center where he practices. Why are men’s urinary problems not just a matter of prostate size? How can natural strategies alleviate urinary difficulties without the need for surgery or drugs? Besides saw palmetto, what nutraceuticals can benefit men with urinary problems? Are there really natural herbal alternatives to testosterone? For men with prostate cancer who are under active surveillance, is there anything more that can be done to minimize their chance of eventually needing surgery or radiation? What nutraceuticals, vitamins and minerals have anti-prostate cancer potential?

Dr. Robert Verkerk, the Executive Director of the Alliance for Natural Health (ANH), discusses a wide range of topics, including the intersection of high-tech medical advances and natural therapies. Dr. Verkerk explains the mission of ANH, emphasizing the defense of health freedom and the promotion of natural approaches to health. They delve into various initiatives that ANH is working on, such as defending access to natural thyroid, reversing bans on important supplements like NMN and NAC, and challenging FDA regulations that restrict information on the benefits of natural products. The episode also highlights the importance of maintaining a balanced approach to healthcare and the ongoing efforts to reform regulatory frameworks that favor pharmaceutical interventions over natural alternatives.

Q&A with Leyla, Part 1: Determining Your Healthy Weight

• A closer look at plasmalogens
• Determining your healthy weight
• I’m having tight, painful cramps in my thighs while sleeping as well as standing after driving my car. Is this from dehydration?

Q&A with Leyla, Part 2: Post-Exercise Pain

• Exercise—for those who hate exercise
• Dealing with post-exercise pain and fatigue
• Is there any treatment for Primary Progressive Aphasia?

In this episode of the Intelligent Medicine podcast, host Dr. Ronald Hoffman discusses the increasing prevalence of depression and anxiety, particularly among young people, with guest Dr. Jacob Teitelbaum, Integrative Medicine physician, researcher, and best-selling author. They explore potential causes, including societal factors, diet, sleep patterns, and the fear-inducing media environment. Dr. Teitelbaum shares insights from his expertise in both conventional and integrative medicine, emphasizing the role of nutritional support, such as magnesium, B vitamins, and curcumin, as well as the importance of psychological strategies, biophysical techniques like shaking off trauma, and natural remedies. They also delve into the potential benefits of alternative therapies like CBD, ketamine, and psychedelics for mental health conditions. Listeners are encouraged to consider a comprehensive approach to managing these pervasive mental health issues.

Jane Jansen, a natural and holistic practitioner from the Tree of Life Wellness Center in Massachusetts, focuses on the importance of the microbiome, particularly the role of probiotics, in maintaining health at all life stages. They explore the benefits of specific probiotic strains, the impact of prebiotics and postbiotics, and the use of Dr. Ohhira’s Probiotics. Topics also include the relationship between the microbiome and mental health, the implications of commonly used medications like Tylenol on gut health, and practical advice for maintaining a healthy gut during travel and holiday seasons.

Part 1: New Testosterone Support

How the low-fat food craze of the 80s set Gen X women up for an astounding rate of ultra-processed food addiction; Is there a replacement for scarce Wobenzyme for vein blood clots? Wrong type of vitamin D may shortchange body of its immune benefits; Beyond “gas station Viagra”—new testosterone support supplement harnesses safe, natural ingredients.

Part 2: Cannabis Extract vs. Low Back Pain

Synthetic progestogens hike risk for brain tumors, natural progesterone safe; Healthy microbiome, good genes, clean lifestyle propel world’s oldest woman to age 117; Can you take too much selenium? Cannabis extract scores vs. low back pain; Can vitamin K prevent breast calcifications? Are we making progress vs. pancreatic cancer? 

References & Resources

Why GenX women can’t stop eating ultra-processed foods
Addiction, 2025; DOI: 10.1111/add.70186

Vitamin D supplements may lower your level of one type of vitamin D
Nutrition Reviews, 2025; DOI: 10.1093/nutrit/nuaf166 

Cannabis extract found to be effective for lower back pain
By Olivia Goldhill, New Scientist  September 29, 2025

Acute selenium toxicity associated with a dietary supplement
Arch Intern Med. 2010 Feb 8;170(3):256-61.

World’s oldest person had a young microbiome and ‘exceptional genome’
By James Woodford, New Scientist.  September 25, 2025

Use of progestogens and the risk of intracranial meningioma: national case control study
BMJ 2024;384:e078078

Part 1: The Secrets of the World’s Oldest Woman

• The secrets of the world’s oldest woman at 117: The microbiome and good genes as determinants of longevity
• What are your thoughts on plasmalogens?
• Our 24-year-old son has recently been diagnosed with Crohn’s disease – help!

Part 2: Excessive Sweating

• My most recent coronary calcium score is 1200. What are your recommendations?
• My husband has been sweating like crazy during our walks. What may be causing this?
• How serious is RSV for seniors? What about healthy seniors?

In this episode of the Intelligent Medicine podcast, Dr. Ronald Hoffman delves into the critical role of mitochondria in overall health with a particular emphasis on skincare with Dr. Julie Faitg, a mitochondrial biologist and senior manager of Applied Research and Regulatory Affairs at Timeline. The discussion highlights the broad impacts of mitochondrial health on lifestyle, diet, sleep, exercise, and psychological well-being. Focusing specifically on Urolithin A (MitoPure), they explore its promising benefits for muscle strength, endurance, and skin health through cellular renewal processes like mitophagy. Dr. Faitg emphasizes the clean formulation and clinical effectiveness of Timeline’s various supplements and skincare products, underscoring their role in extending healthspan and rejuvenating skin from the outside in. The episode provides practical insights on product usage and the broader implications of mitochondrial science for anti-aging and wellness.

This episode of the Intelligent Medicine podcast is a deep dive into the complexities of Lyme disease and other tick-borne illnesses. Nicole Bell, the CEO of Galaxy Diagnostics and author of “What Lurks in the Woods,” details the challenges of diagnosing tick-borne diseases, the limitations of current diagnostic tests, and the controversy around treatment methodologies. Nicole shares her personal journey that led her to this field after her husband was misdiagnosed with early-onset Alzheimer’s, which was later revealed to be caused by advanced Lyme disease. They also discuss new diagnostic techniques, the importance of personalized treatment plans, and ongoing advocacy efforts to improve awareness and research funding for Lyme disease.