Q&A with Leyla, Part 1: Soup in Cold Weather

• Soup in cold weather
• Study: No benefit from beta-blockers post heart attack, but vitamin D cuts risk of 2nd heart attack in half!
• New study links oxalic acid to gadolinium side effects and toxicity
• More on the assault on young people’s brains

Q&A With Leyla, Part 2: Water Filters

• What can I do about a hip labrum tear?
• Are there any specific water filters that you recommend?
• What say you about lead levels in dark chocolate?

Clinical Pharmacist, Author, Board-Certified Clinical Nutritionist, and Health Expert Jim LaValle details the many health benefits of aged garlic extract, particularly its impact on periodontal disease. He reveals exciting new research findings that show Kyolic Aged Garlic Extract supplements can significantly reduce periodontal pocket depth — a key indicator of gingivitis and periodontal disease progression. He also highlights the role of aged garlic extract in reducing inflammation and improving gum health, which in turn has significant implications for cardiovascular and cognitive health. The conversation also touches on various formulations of aged garlic extract available from Kyolic, the importance of integrative approaches to health and wellness, and updates on the latest trends in anti-aging medicine, including peptides and GLP-1 agonists.

Nathan Jones, CEO of Xlear, Inc., details the benefits of xylitol in dental and respiratory health products such as nasal sprays and chewing gums under the Spry brand. Nathan advocates for the FDA to allow anti-cavity claims for xylitol and other compounds despite the current monopoly of fluoride in such claims. They question the efficacy and potential downsides of fluoride, and explore alternative dental health interventions. The episode also covers xylitol’s role in preventing tooth decay, respiratory health benefits during the COVID-19 pandemic, and ongoing legal challenges with the FTC. Discussions highlight the potential implications of oral health on systemic diseases like cardiovascular disease and Parkinson’s, and emphasize the importance of nasal hygiene alongside dental care.

Part 1: Benefits of Cocoa Flavanols

“Study” that’s not even a study spreads panic about dubious melatonin-heart failure link; Should you ignore Dr’s advice to take powerful acid-blocking drugs? Novel implantable electrical pacemakers may bring relief to sufferers of severe constipation; Benefits of cocoa flavanols for heart, brain, athletic performance. 

Part 2: Coffee and Atrial Fibrillation

The FDA belatedly liberates women’s hormone replacement; Beta-blockers now deemed passé for routine heart attack aftercare; After most breast cancer surgery, adjuvant radiation brings no survival benefits; Can you drink caffeinated coffee if you have atrial fibrillation? Ignore frequent falls without attention to balance and stability training at your peril; Is it reasonable to contemplate a knee replacement surgery at 88? 

References & Resources

Melatonin as a novel drug to improve cardiac function and quality of kid in heart failure patients: a systematic review and meta-analysis.
Clinical Cardiology. 2025 Mar;48(3):e70107. doi: 10.1002/clc.70107.

A study questions melatonin use and heart health, but lose sleep over it
By Lauren Neergaard, Associated Press  November 7,2025

Burst-patterned stimulation restores colonic motility in preclinical models
Sci Transl Med. 2025 Nov 5;17(823):eadu4615. doi: 10.1126/scitranslmed.adu4615. Epub 2025 Nov 5. PMID: 41191773.

Speaking multiple languages may slow down biological aging
Nat Aging 5, 2340–2354 (2025). https://doi.org/10.1038/s43587-025-01000-2

Cup of coffee a day may not be harmful for some adults with AFib and could lower episodes
American Heart Association Scientific Sessions 2025 Late-Breaking Science Abstract 4377429

RADIATION may be unnecessary for many breast cancer patients
N Engl J Med 2025;393:1771-1783

Beta blockers have no effect on heart attack patients
N Engl J Med 2025 Aug 30 Ibanez B et al. N Engl J Med 2025 Aug 30

Marty Makary: The FDA liberates women’s hormone replacement therapy
By Marty Makary. WSJ  November 10, 2025

Q&A with Leyla, Part 1: Are children’s IQs going down?

• Are children’s IQs going down?
• An overview of medical reversals
• Can you comment on the melatonin and heart failure study?
• Result of a prostate artery embolization

Q&A with Leyla, Part 2: The State of our Healthcare System

• I have hypothyroidism.  Do I need to be concerned about low ferritin levels?
• What are the benefits of lower-dose fish oil?
• Is there a connection between melatonin supplementation and depression?
• Can I take melatonin while on warfarin?
• What to do about the state of our healthcare system?

Fertility specialist Gabriela Rosa, the CEO and founder of the Rosa Institute, discusses the decline in fertility rates, the experiences of couples struggling to conceive, and the multifaceted methods used to address this issue. Gabriela shares her journey of merging conventional and holistic fertility sciences, citing real-life cases of couples who succeeded in conceiving after addressing underlying health issues. They delve into the importance of lifestyle factors, such as diet, exercise, and mental health, and discuss specific interventions like hormone management and supplements. The conversation also covers environmental influences, the role of metabolic health, and the critical importance of personalized treatment plans for couples facing infertility. Gabriela provides insights on how to balance high-tech and holistic approaches to optimize fertility outcomes.

Neil Levin, Senior Nutrition Education Manager and product formulator for Now Foods and Protocol for Life Balance, discusses the importance of targeted nutrients for women’s health. They delve into various supplements such as magnesium, myo-inositol, progesterone cream, D-Mannose, and biotin, explaining their benefits for conditions like PCOS, blood sugar regulation, menstrual migraines, urinary tract infections, and overall skin, hair, and nail health. The conversation also touches on the importance of tailoring nutrients to individual needs and the role of personalized nutrition in supporting women’s health amidst modern stresses.

Part 1: 4 Simple Lifestyle Measures Deliver 9 Additional Years of Disease-Free Healthspan

Just 4 simple lifestyle measures deliver 9 additional years of disease-free healthspan; Study underscores protein’s role in staving off cancer, heart disease, and death; CoQ10 scores vs. neurodegeneration; Urolithin A (Mitopure®️) found to support athletic performance, immune function; Why you should ignore some influencers’ advice to avoid fish oil. 

Part 2: New Non-Invasive Option for Men’s Age-Related Urinary Problems

As little as 3000 steps per day can slow progression to Alzheimer’s Disease; Self-reports of memory impairment soaring among young people; New study vindicates unprocessed red meat—and even often-vilified processed red meat—for cancer and overall health. Prostate artery embolization (PAE) offers new non-invasive option for men’s age-related urinary problems; Targeting the mitochondria and the microbiome for Parkinson’s Disease; Popular prostate and hair loss prevention drugs linked to depression and suicide—while Cialis for urinary symptoms may stave off cardiovascular disease; Discovery that a safe, cheap medication may increase survival after breast cancer surgery. 

References & Resources

Coenzyme Q10 attenuates age-associated neurodegeneration via modulation of autophagy and neuroinflammation in aged rats
Metab Brain Dis. 2025 Nov 3;40(8):305. doi: 10.1007/s11011-025-01721-8.

Effect of the mitophagy inducer urolithin A on age-related immune decline: a randomized, placebo-controlled trial
Nat Aging. 2025 Nov;5(11):2309-2322.

Dietary intake of total, animal, and plant proteins and risk for all-cause, cardiovascular, and cancer mortality: systematic review and dose-response meta-analysis of prospective cohort studies
BMJ 2020;370:m2412

Association of healthy lifestyle with years lived without major chronic diseases
JAMA Intern Med. 2020;180(5):760–768. doi:10.1001/jamainternmed.2020.0618

Unprocessed red meat and processed meat consumption: dietary guidelines recommendations from the Nutritional Recommendations (NutriRECS) Consortium
Annals of Internal Medicine Volume 171, Number 10

Long-term effects of phosphodiesterae-5 inhibitors on cardiovascular outcomes and death:a systematic review and meta-analysis
Eur Heart J Cardiovasc Pharmacothe. 2024 Aug 14;10(5):403-412.

Popular hair-loss pill linked to depression and suicide
J Clin Psychiatry 2025;86(4):25nr15862

Oral bacteria may trigger Parkinson’s Disease
Neuroscience News, September 22, 2025

Scientists just shattered a major exercise myth
Advances, 2025; 4 (10): 102140 DOI: 10.1016/j.jacadv.2025.102140

Physical activity as a modifiable risk factor in preclinical Alzheimer’s disease
Nature Medicine Published: 03 November 2025

Alarming surge in memory problems among young adults
Neurology, 2025; 105 (8) DOI: 10.1212/WNL.0000000000214226

Q&A with Leyla, Part 1: Melatonin for Bone Mineral Density?

• More on gadolinium effects and detox
• I was found to have a small pericardial effusion. What advice can you give me?
• Is melatonin beneficial for bone mineral density? If so, how much should I take?

Q&A with Leyla, Part 2: Coffee Enemas for Liver Detox?

• Study: Mitopure’s impact on immune parameters
• What important blood tests should one get, and what are the ideal levels to look for?
• I do coffee enemas for liver detox. How many can I do per week?  
• I’ve been on Metformin and lost some weight. Should I increase my dose to lose more?
• Could a recent dental implant be causing clogged ears and a hissing noise?

Marina Pavlovic Rivas, co-founder and CEO of Eli Health, reveals a revolution in personal health monitoring through advanced wearable devices. They discuss the journey from primitive step counters to sophisticated devices, such as continuous glucose monitors (CGMs) and the world’s first instant hormone monitoring system by Eli Health. The conversation delves into the new cortisol testing kit from Eli Health, exploring its implications for understanding stress, sleep, metabolism, and overall health. Rivas explains the process of using the device, its integration with a smartphone, and how AI helps interpret the hormone data for actionable insights. Future plans for Eli Health’s hormone monitoring technology, including progesterone and testosterone, are also discussed, offering a glimpse into the evolving landscape of self-monitoring and personalized health.