Dr. Sina McCullough, author of “Hands Off My Food! How to Defend Your Food, Health, and Freedom,” argues that bureaucrats, multinational biotech corporations, and regulatory loopholes have helped adulterate the U.S. food supply. McCullough describes nearly dying from rheumatoid arthritis after years of worsening symptoms despite a “clean” organic, paleo-style diet, then recovering through functional testing that revealed 15 nutrient deficiencies, food sensitivities, and arsenic poisoning; she says she healed without pharmaceuticals. She explains that nutrition training often ignores food adulterants and claims the FDA facilitates markets rather than ensures safety, highlighting the GRAS loophole, voluntary notification, lack of long-term and cumulative testing, and industry influence via the revolving door. Examples include trans fats, glyphosate formulation issues, gene-edited crops, and recombinant bovine growth hormone approvals and labeling. She discusses organic loopholes and emphasizes solutions: read labels, “feed the good and starve the bad,” vote with purchasing, seek third-party certifications, and know your farmer; she also promotes her Beyond Labels podcast with farmer Joel Salatin.

Part 1: A New, Enhanced Form of Fish Oil

Social media and AI—the digital equivalents of ultra-processed junk food–are undermining our brain power; Are natural non-caloric sweeteners—erythritol, xylitol and stevia—safe? A pig’s brain has been flash frozen, and reanimated, signaling new prospects for cryopreservation after death; Dr. Jeffrey Bland weighs in on a new, enhanced form of fish oil from Big Bold Health.

Part 2: The Ultimate Weight Loss Plan—The Boring Diet

Heart Association clashes with RFK, Jr., doubles down on recommendation for low-fat diets; Why the evidence for meat and full-fat dairy avoidance is weak; What are the health benefits of circumcision? The ultimate weight loss plan—the Boring Diet; Substituting famotidine for PPIs for reflux; Midlife vitamin D curbs Alzheimer’s risk; Natural support for polymyalgia rheumatica; What teens eat could be affecting their mental health.

Q&A with Leyla, Part 1: Dr. Hoffman’s New Zealand Bike Trip

• Highlights from Dr. Hoffman’s New Zealand bike trip
• Do you prefer whey protein isolate or concentrate?
• My liver enzymes went up taking a statin drug. My doctor recommends I take milk thistle. What are your thoughts?
• If any supplement protocols are out of stock, should we make substitutions?

Q&A with Leyla, Part 2: Farmed v. Wild Caught Seafood

• What are your thoughts on peptides?
• So it’s not possible to get enough protein from plants only?
• What about the downsides to animal protein?
• Are there any negative reports on the usage of extra virgin olive oil?
• Is it true that the nutritional value of farmed seafood is the same as wild caught?

Dr. David Clarke, president of the Psychophysiologic Disorders Association, details the link between stress and chronic pain and the scope of brain-generated symptoms. Clarke says many patients have symptoms not explained by disease or injury, estimating about 20% of U.S. adults (about 50 million) live with chronic pain, with costs estimated at $650 billion, and notes clinicians are often not trained to evaluate psychosocial stressors. He describes clues that pain is brain-generated (e.g., multiple long-lasting or shifting symptoms, lack of objective nerve damage) and a broad symptom spectrum from migraines and IBS to pelvic pain and rashes. Clarke discusses adverse childhood experiences, triggers, personality traits, and repressed emotions, cites randomized trials showing “pain relief psychology” can reduce pain and change MRI findings, and shares resources including a clinician directory, self-assessment quiz, and the Curable app. 

How Continuous Glucose Monitors Can Optimize Metabolic Health—and Where GLP-1 Drugs Fit: Emergency physician-turned-preventive/metabolic medicine specialist Dr. Paul Kolodzik of Metabolic MD reveals how continuous glucose monitors (CGMs) are a tool not only for diabetics but also for non-diabetics and pre-diabetics to personalize diet, sleep, and exercise by seeing real-time glucose patterns instead of relying on fingersticks or A1c averages. Kolodzik describes CGM use in his clinic (two-week diagnostic wear, then therapeutic guidance), highlights insulin resistance, fasting insulin testing, glucose variability, and the role of low-carb eating, intermittent fasting, and strength training to improve metabolic syndrome, triglycerides, and fatty liver. They discuss CGM sourcing/cost, device mechanics and accuracy, possible future noninvasive wearables, and GLP-1/GIP weight-loss drugs, emphasizing supervised, limited-dose use with protein and lifestyle changes to avoid muscle loss and weight regain. A free PDF of Kolodzik’s book is offered HERE.  

Part 1: Are eggs good or bad for the brain?

Are eggs good or bad for the brain? Low levels of a key nutrient can foster anxiety; Dealing with muscle cramps that develop hours after exercise; Garlic mouthwash outperforms chemical antibacterials; 76% of the world’s population aren’t getting enough omega-3s; Surgery may hasten progression to Alzheimer’s, but a vitamin may help; After marijuana legalization, some states want a do-over.

Part 2: Hobbies may forestall all-cause mortality—by 29%!

The pros and cons of natural vs synthetic vitamins; Telehealth site for ADD meds lands founder in prison; Why eradicating H. pylori may set the stage for Alzheimer’s; Why integrative physicians often don’t accept insurance; Far-infrared phototherapy may offer “electroceutical” treatment for dementia; Hobbies may forestall all-cause mortality—by 29%! 

Part 1: Spelt Matzoh v. Traditional Wheat Matzoh

• Half of US adults are interested in GLP-1 agonists for weight loss
• Is spelt matzoh better than traditional wheat matzoh for Passover?
• Is a dry red wine preferable to sweet wine or grape juice?
• Is Einkorn flour a better alternative to modern wheat?
• Which liver support supplements are best for alcoholic issues?

Part 2: Tingling After a Shingles Outbreak

• I was diagnosed with Exocrine Pancreatic Insufficiency. Which digestive enzymes are best to take?
• I still have pain and tingling after a shingles outbreak. What can I take for it?
• So many protein shakes contain carrageenan, but isn’t it a carcinogen?
• My 5-year-old grandson has pancolitis.  Do you have any recommendations?
• What do you think of an organic acids test for chronic fatigue?
• How can I find the cause of my atopic dermatitis?  

Oral Health, Inflammation, and Periodontal Disease: Dr. William Levine, a board-certified periodontist and chief scientist at Peri Active Oral Rinse, offers a deep-dive on periodontal disease as an infectious inflammatory condition with autoimmune-like tissue destruction. It affects over 50% of U.S. adults over 35 and rises with age. He details bidirectional links between gum disease and systemic conditions, including cardiovascular disease, stroke, diabetes, and some dementias, and notes signs such as bleeding, pain, swelling, loose or shifting teeth, and gum recession. Levine explains plaque, dysbiosis, and biofilms, emphasizing mechanical plaque removal to preserve a healthy oral microbiome. Standard care includes scaling and root planing, possible surgery, and lasers; antiseptic rinses like chlorhexidine can be harsh and limited against biofilms. Levine describes a plant-bioactive rinse (gotu kola, echinacea, elderberry) designed to reduce harmful bacteria, penetrate gums, lower inflammation, and promote repair; xylitol may help via saliva stimulation. He also addresses smoking, dry mouth, fluoride toothpaste, interdental cleaning, and osteoporotic drugs’ dental risks.

Herbal Medicine, Quality Control, and Adulteration Prevention: Mark Blumenthal, founder and executive director of the American Botanical Council (ABC), recounts his entry into herbalism via vegetarianism in 1968, off-grid living, and starting a wholesale herb business in 1974 before shifting to nonprofit education, research, advocacy, and quality control. The discussion covers the evolution from teas and tinctures to standardized extracts, the complexity and synergy of multiple constituents, and how standardization supports quality control and therapeutic consistency. Blumenthal explains ABC’s Botanical Adulterants Prevention Program and its free, peer-reviewed resources addressing global fraud, plus GMP requirements and laboratory methods for identity, contamination, and potency testing. He discusses herbs including ashwagandha, turmeric/curcumin and adulteration risks, maca, nigella, and milk thistle, and outlines ABC resources, HerbClip, and membership options at herbalgram.org.

Intelligent Medicine Radio for March 21, Part 1: Alpha-Gal Syndrome

New weight loss drugs may portend end of “Fat Acceptance” movement; Celebs and Southerners embrace GLP-1s; Trump clears path for more access to diet drugs; Mid- and late-life exercise slash dementia risk; “Ethicists” urge more tick-borne meat allergy to save planet—as alpha-gal syndrome claims first fatality; What’s wrong with the melatonin study that claims it leads to heart failure? How to detox 9-11 first-responders? Can weekend warriors obtain same benefits as regular exercisers? 

Intelligent Medicine Radio for March 21, Part 2: Can surgical anesthesia accelerate memory loss?

Can natural herbs aid recovery from anorexia? What an analysis of Hitler’s DNA tells us about how genes shaped his personality; Can surgical anesthesia accelerate memory loss?  Bananas could be interfering with your smoothie’s health benefits; Not just sun, but pesticides and herbicides increase risk for melanoma; Chemical residues on produce impair male fertility; Proliferation of fast-paced social media videos are dumbing us down; Doctors aren’t less resilient, the demands of medicine are just fostering unprecedented levels of physician burnout.