Longevity Unlocked: Understanding the Impact of Mitophagy

Unlocking Mitochondrial Health: Exploring Urolithin A and Mitochondria-Boosting Supplements with Dr. Brad Currier, a senior scientist and manager of clinical trials at Timeline, a Swiss biotech company known for their product MitoPure. The conversation delves into a unique compound, Urolithin A, which is derived from pomegranates and identified as a key activator of mitophagy—the cellular process of recycling and rejuvenating damaged mitochondria. Dr. Currier elaborates on the significant health benefits of Urolithin A, including improved muscle strength, enhanced immune function, and its potential cognitive and anti-aging effects. The episode also covers topics such as the role of exercise and dietary protein in maintaining muscle health, the future potential of supplementary compounds like creatine, and highlights the newly introduced MitoPure gummies designed for convenient daily intake. Additionally, the discussion extends to the implications of mitochondrial function in various tissues, including skin and hair health.














Intelligent Medicine Radio for January 10: Long-Overdue Change to the Broken Food Pyramid

Intelligent Medicine Radio for January 10, Part 1: Long-Overdue Change to the Broken Food Pyramid

Applauding a long-overdue change to the broken Food Pyramid; Vitamin C enhances skin health, protects against environmental pollutants; FDA green lights testosterone replacement; Does CoQ10 protect against statin muscle damage? The story of America’s first vitamin pioneer; Millions of America’s seniors take 8 or more prescription drugs simultaneously. 



Intelligent Medicine Radio for January 10, Part 2: Is just a little red wine every day bad for you?

MAHA derailed by federal policies that allow harmful chemicals to proliferate; 25 years later, a study that exonerated glyphosate has been retracted due to undue influence from Monsanto; Judge blocks W. Virginia artificial food dye and additive ban; New refined criteria would raise US obesity rate to nearly 70%; FDA approves electrical stimulation headset as safe and effective for home-use to treat depression; Accidental toxic fume releases on planes cause long-term disability, deaths, in passengers and crew. “Digital pacifier” screen time for toddlers found to hike risk for adolescent focus problems, anxiety; Is just a little red wine every day bad for you?












Q&A with Leyla: Top Stories of 2025

Q&A with Leyla, Part 1: Top Stories of 2025

  • Top stories of 2025
  • Does the use of statins lead to muscle loss?
  • I have mitral valve prolapse with regurgitation. Should I increase my supplement dosages?



Q&A with Leyla, Part 2: GABA for insomnia and sleep support?

  • Could you discuss GABA for insomnia and sleep support?  Are there long-term health benefits?
  • What impact does a cocktail of pharmaceutical drugs have on the microbiome?
  • Can I take more than 2 daily doses of Dr. Ohira’s probiotics?
  • Which is the correct estrogen to take in HRT?  Estriol or estradiol?
  • In light of the recent EPA proposal to double permissible formaldehyde emissions, how does this jibe with MAHA?












Exploring Nutritional and Natural Approaches to Parkinson’s

Innovative Approaches to Parkinson’s Disease with Dr. Heather Zwickey, Vice President of Research and Academic Excellence, Provost, and Professor of Immunology at the National University of Natural Medicine (NUNM), and author of “Eating Better for Parkinson’s: A Nutritional Starter Guide.” She delves into innovative treatments for Parkinson’s disease, including the role of diet, particularly a ketogenic diet, and the impact of the gut microbiome. Dr. Zwickey shares her inspiration from NBA player Brian Grant’s experience with Parkinson’s and discusses her small study on the feasibility of a ketogenic diet, showing promising results. She also details other potential treatments like supplements, exercise, particularly boxing and dancing, environmental factors, and even cannabis. Dr. Zwickey highlights the importance of personalized approaches due to varying individual responses to treatments.














Decoding Chronic Illness: Environmental Triggers and Solutions

Understanding and Treating Complex Illnesses with Dr. Neil Nathan, author of “Toxic 2nd Edition: Heal Your Body from Mold Toxicity, Lyme Disease, Multiple Chemical Sensitivities, and Chronic Environmental Illness.” Dr. Nathan shares his expertise on the multifaceted nature of chronic illnesses, which often defy simple categorization and may be misdiagnosed as psychiatric issues. The discussion covers the impact of environmental toxins, electromagnetic fields, and infections like Lyme disease and long COVID. Dr. Nathan also highlights the importance of understanding inflammation’s complex pathways and offers suggestions for both elimination of root causes and restoration of immune system functionality. The episode provides insights into new diagnostic tools and treatment methodologies for persistent and intrusive health issues.














ENCORE: Intelligent Medicine Radio for January 3: Artificial Light and Menstrual Cycle Rhythms

Part 1: Artificial Light and Menstrual Cycle Rhythms

The advent of artificial light is obliterating women’s moon-driven menstrual cycle rhythms; When the triple whammy of cataracts, glaucoma, and macular degeneration strikes; Why can systolic blood pressure spike erratically? Are wrist and finger wearables for blood pressure ready for prime time? Nearly half of drivers killed in crashes have THC in their blood; Drinking bottled water causes surge in plastic micro-particle intake; The common supplement that can supercharge cancer immunotherapy.



Part 2: Psychological Benefits from Grandparent Time

Examining the claim that cabbage family vegetables are bad for the thyroid; Walmart announces sweeping move to reformulate its products without synthetic dyes, sketchy additives; Under Congressional questioning, Google admits to censoring contrary narratives on YouTube during Covid; Children garner psychological benefits from grandparent time; J&J fined nearly $1 billion in landmark talc baby powder lawsuit; Humans are among the few animals who can’t make their own vitamin C—why that may be a good thing.









References & Resources

A common supplement could supercharge cancer treatments
Cell Reports Medicine, 2025; 6 (9): 102324 DOI: 10.1016/j.xcrm.2025.102324

Synchronization of women’s menstruation with the moon has decreased but remains detectable when gravitational pull is strong
Science Advances, September 24, 2025

More marijuana users are crash dummies
By the Editorial Board,  WSJ  Oct 8, 2025

New research reveals what’s really hiding in bottled water
Journal of Hazardous Materials, 2025; 495: 138948 DOI: 10.1016/j.jhazmat.2025.138948

Do not use unauthorized devices for measuring blood pressure: FDA safety communication
www.fda.gov, September 16, 2025

Nearly half of drivers killed in crashes had THC in their blood
Scientific Forum, American College of Surgeons (ACS) Clinical Congress 2025.

Walmart U.S. moves to eliminate synthetic dyes across all private brand food products
Rheuter, October 1, 2025

The real reason why we lost the ability to make vitamin C
By Michael LePage, NewScientist  August 12, 2025

Johnson and Johnson ordered to pay $966 in Mae Moore baby powder cancer lawsuit
By Diana Novak Jones, Reuters Oct 7, 2025

Do Brassica vegetables affect thyroid function? A comprehensive systematic review
Int J Mol Sci.  2024 Apr 3;25(7):3988. doi: 10.3390/ijms25073988.

Google on Tuesday admitted to censoring YouTube content that questioned official COVID 19 narratives and deplatforming users who posted such material—under pressure from the Biden administration 
This is a YouTube video




ENCORE: Q&A with Leyla: A Treatment for Warts

Q&A with Leyla, Part 1: Aging

  • Consequences of weight loss with weight loss drugs…
  • Enter myostatin inhibitor drugs
  • My latest HgbA1c is 5.9, and I’m doing everything right. What gives?
  • I’m approaching 80. Could you discuss aging?



Q&A with Leyla, Part 2: A Treatment for Warts

  • What are your thoughts on Alpha-ketoglutarate for healthy aging?
  • A treatment for warts?
  • Am I destined to develop diabetes given my strong family history of diabetes and high blood pressure?












ENCORE: Q&A with Leyla: Holiday Stress

ENCORE: Q&A with Leyla, Part 1: Holiday Stress

  • Holiday Stress tops tax season stress
  • What would Dr. Hoffman say?
  • Is berberine truly efficacious?
  • My doctor recommends I drink alcohol to reduce stress and improve circulation



ENCORE: Q&A with Leyla, Part 2: Thiamine for Parkinson’s?

  • What do you think of thiamine as a treatment for Parkinson’s?
  • Is there a natural thyroid medicine you recommend that is not pork-derived?
  • Please discuss the COVID-19 vaccine and cardiology issues
  • Can you help my granddaughter with guttate psoriasis?












ENCORE: Q&A with Leyla: The Holiday Season in NYC

ENCORE: Q&A with Leyla, Part 1: The Holiday Season in NYC

  • The Holiday Season in NYC
  • Peanut allergies cause and effect
  • Which calcium supplements can I take if I’m allergic to cow protein?
  • Can my husband take saw palmetto in lieu of his prostate medications?
  • What do you think of traction to help bulging discs?
  • What is your take on green powder supplements?



ENCORE: Q&A with Leyla, Part 2: Reducing Coronary Plaque

  • What do you think of serrapeptase for reducing coronary plaque?
  • We were told to get a TDAP vaccine or we wouldn’t be able to see our new grandchild for 8 weeks!
  • Do I have lupus?
  • Which supplements tend to reduce negative effects of X-rays?












ENCORE: Intelligent Medicine Radio for December 27: French Fries’ Diabetes Risk

Part 1: French Fries’ Diabetes Risk

RFK Jr. issues sharpest ultimatum yet to medical schools: “Start teaching nutrition now or face penalties!” Fast-food outlets continue to abound in teaching hospitals; Once serious causes of flank pain are ruled out, patients are often left to fend for themselves; Potatoes don’t increase risk of diabetes—unless you eat French fries; Deep-frying in seed oils can yield harmful byproducts—but so, too, when you substitute with lard; As doctors get more aggressive treating blood pressure, how to minimize medication side effects; New study shows beetroot juice can lower BP by 7 points.



Part 2: Breakthroughs in Rheumatoid Arthritis Treatment

For weight loss, complete avoidance of ultra-processed foods outperforms mere “healthy diet” comprising minimally-processed items; Research fraud undermines anti-dementia drug pipeline; Comprehensive lifestyle modification program scores against cognitive decline; Women’s brains especially vulnerable to Omega-3 deficiencies; Bible says “Lame shall walk again” and 21st century science may soon bring about this miracle; Breakthroughs in rheumatoid arthritis treatment.









References & Resources

RFK Jr.: An Apple a day is a good prescription
By Robert F. Kennedy Jr., WSJ  Aug 27, 2025

Fast-food outlets in hospitals affiliated with US medical schools
Am J Lifestyle Med. 2024 Sep 4:15598276241267252. doi: 10.1177/15598276241267252

New ACC/AHA hypertension guidelines still urge early treatment but with some twists
By Yael L Maxwell, tctMD  Aug 14, 2025

What scientists discovered about French fries and diabetes
BMJ, 2025;390:e082121 DOI: 10.1136/bmj-2024-082121

Deep frying cooking oils promote the high risk of metastases in the breast – A critical review
Food and Chemical Toxicology  Volume 144, October 2020, 111648

Beetroot juice’s blood pressure secret: the nitrate effect
by Maria Weib, Medscape Medical News  August 20, 2025

Autoxidation of cholesterol in tallows heated under deep frying conditions: evaluation of oxysterols by GLC and TLC-FID
Lipids. 1986 Jun;21(6):383-7. doi: 10.1007/BF02534932. PMID: 3736347

Secretaries Kennedy, McMahon demand comprehensive nutrition education reforms
Department of Health and Human Services  August 27, 2025

3-5 cups of coffee a day linked to longer life, lower diabetes risk
By Jessica Freeborn,  Medical News Today, August 26, 2025

A startling omega-3 deficiency may explain women’s Alzheimer’s risk
Alzheimer’s, 2025; 21 (8) DOI: 10.1002/alz.70512

People can lose more weight by avoiding ultra-processed food
By Allice Callahan, NYTimes Well Newsletter August 4, 2025

People can lose more weight by avoiding ultra-processed food
Nat Med (2025). https://doi.org/10.1038/s41591-025-03842-0

Structured vs self-guided multi-domain lifestyle interventions for global cognitive function
JAMA. 2025;334(8):681–691. doi:10.1001/jama.2025.12923

Questionable papers underpin other drugs
By Charles Piller, Science.org  September 26, 2024

Rats walk again after breakthrough spinal cord repair with 3D printing
Advanced Healthcare Materials, 2025; DOI: 10.1002/adhm.202404817