Part 1: Chronic Leg Swelling

Natural alternatives for Trump’s chronic leg swelling problems; How certain blood and urine tests can help predict osteoporosis; Dark chocolate enhances cognitive function—with lasting effects; caffeinated black coffee reduces risk of death by 14%; NY Times misses the boat again on supplements for immunity; Man dies after being pulled into MRI machine.

Part 2: Can mammograms cause cancer?

The dark personality traits that underlie online political engagement; Parents’ use of topical hormone preparations may pose unusual risks to their babies; Alternative to beta blockers for high blood pressure; Does lecithin lower cholesterol? Caloric restriction may extend life—but at what cost? A high-fiber diet may mimic caloric restriction’s longevity benefits; Can mammograms cause cancer? 

References & Rescources

Can vitamins C and zinc actually boost your immune system?
By Katie Mogg, New York Times, March 3, 2025

Man dies after being pulled into MRI machine while wearing metal chain
By Meredith Deliso, abcnews.go.com  July 18, 2025

Making best use of bone turnover markers to monitor oral bisphosphonate therapy
Cleveland Clinic Journal of Medicine January 2023, 90 (1) 32-34

Black coffee, longer life: The science behind your morning perk
The Journal of Nutrition, 2025; DOI: 10.1016/j.tjnut.2025.05.004

Sub-chronic consumption of dark chocolate enhanced cognitive function and releases nerve growth factors: A parallel-group randomized trial
Nutrients. 2019 Nov 16;11(11):2800.

FoMO and dark personalities drive online political engagement
Neuroscience News  July 21, 2025

A high-fiber diet mimics aging-related signature of caloric restriction in mammals
Nat Commun 16, 5917 (2025). https://doi.org/10.1038/s41467-025-61046-z

Potential downsides of calorie restriction
Nat Rev Endocrinol 21, 427–440 (2025)

Baby girl grows ‘micropenis’ after lying on dad’s chest
By McKenzie Beard, NY Post, July 22, 2025

Influence of soy lecithin administration on hypercholesterolemia
Cholesterol. 2010;2010:824813. doi: 10.1155/2010/824813. Epub 2009 Dec 28

Q&A with Leyla, Part 1: Safe Nonstick Pans?

• Wondering what you think of the supplement Fatty 15?
• Can you recommend any nonstick pans that are safe to use?
• Study finds gut microbes can absorb and help expel forever chemicals like PFAS

Q&A with Leyla, Part 2: Crushing Pills for Easier Swallowing?

• I’m having a hard time swallowing pills.  Can I crush or chew them or does this adversely impact their efficacy?
• Should we all be taking creatine supplements?
• Are certain inflammatory markers associated with chronic fatigue?  What about COVID?
• Can you recommend any non-toxic paints and dehumidifiers to use in my basement?  

Dr. Chris Rhodes, a clinical fasting, longevity, and biomimetics researcher at UC Davis, discusses various fasting methods including time-restricted feeding, intermittent fasting, and prolonged fasting. He highlights the biochemical processes involved, such as autophagy and metabolic adaptation, and underscores the potential health benefits of fasting, which include improved metabolic markers and extended lifespan as evidenced in animal models. Dr. Rhodes also introduces Mimio, a supplement developed from his research designed to mimic the benefits of fasting without actual food deprivation, detailing its composition and the promising clinical results. The discussion weaves through scientific insights, personal experiences, and practical applications of fasting and fasting-mimicking agents.

Judy Karofsky, author of “DISELDERLY CONDUCT: THE FLAWED BUSINESS OF ASSISTED LIVING AND HOSPICE,“ details the myriad issues related to the care of elderly individuals in assisted living and hospice settings. Judy shares personal experiences, including difficulties encountered in securing proper care for her mother, and highlights systemic problems like substandard care, lack of federal regulations, and the challenges posed by private equity’s involvement in the senior care industry. She also outlines possible reforms and solutions, emphasizing the urgent need for federal oversight and better standards to ensure the well-being of seniors. The dialogue offers valuable insights for anyone looking to understand the complexities and necessary improvements in the care of older adults.

Intelligent Medicine Radio for July 19, Part 1: AI-boost for mammograms?

AI-boost for mammograms—a bridge too far? Plastics and heart disease; What does a high CRP mean? Social media marketing of female aphrodisiac dinged with FDA warning; Roundup gets a makeover; Artificial sweeteners may hasten puberty in kids; Plus an encore of our interview with Dr. Jeffrey Bland introducing Himalayan Tartary Buckwheat as a hedge against age-related immune decline.

Intelligent Medicine Radio for July 19, Part 2: Hot Baths v. Saunas

Advice for liver fibrosis; A caller with a 30 year history of fatigue may need adrenal support; Air filters reduce classroom absenteeism; Inhaled insulin may free diabetics from injections; High blood sugar, not just waning testosterone, the culprit in male sexual decline; Hot baths beat saunas for cardiovascular benefits; Monday stress is real—even for retirees.

References & Rescources

New mammography tools — the need for clinically meaningful assessment standards
N Engl J Med 2025;393:211-213

Phthalates exposure from plastics and cardiovascular disease: global estimates of attributable mortality and years life lost
eBioMedicine, Volume 117, 105730

Maker of sexual desire drug Addyi gets FDA warning letter
By Kristen Monaco, MedPage   June 11, 2025

New research shows Monday stress is etched into your biology
Journal of Affective Disorders, 2025; 389: 119611 DOI: 10.1016/j.jad.2025.119611

Blood sugar, not age, drives sexual health decline in men
Neuroscience News  July 13, 2025

Hot tubs vs saunas: Study finds which offers greater health benefits
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2025; 329 (1): R20 DOI: 10.1152/ajpregu.00012.2025

AI sniffs earwax and detects Parkinson’s with 94% accuracy
Analytical Chemistry, 2025; DOI: 10.1021/acs.analchem.5c00908

Sweet but risky: Common sweeteners may be accelerating puberty in kids
ScienceDaily July 15, 2025

Roundup, the popular herbicide, is undergoing a formula change, phasing out glyphosate in some consumer products and replacing it with other active ingredients
By Carey Gillam, The New Lede  October 22, 2024

Inhaled insulin may free children with type 1 diabetes from injections
By Sara Novak, NewScientist  July 10, 2025

Air filters in classrooms reduce sick days by more than 10 per cent
By Michael LePage,  NewScientis  April 29.2025

Q&A with Leyla, Part 1: Do you need to filter your water?

• Do you need to filter your water?
• More on the REMs test for osteoporosis

Q&A with Leyla, Part 2: Ashwagandha

• My husband has high cholesterol, triglycerides, and blood sugar…help!
• Is taking Xifaxin and metronidazole an effective treatment for SIBO?
• I have thyroid antibodies, had COVID twice, and now suffer from fatigue
• I am 83 years old and my symptoms started after taking the second dose of the Pfizer vaccine in 2021.
• I’ve been taking ashwagandha for years for mild anxiety.  Is it okay to continue?

Exploring Innovative Approaches to Pain Management with Dr. Fawad Mian, a neurologist and regenerative medicine specialist. He delves into the various forms of pain and the limitations of traditional treatments such as drugs and surgery. Dr. Mian shares his personal journey with chronic pain and his transition into regenerative medicine. The discussion covers alternative treatments like prolotherapy, platelet-rich plasma (PRP), and stem cell therapies, emphasizing their potential benefits and the importance of image guidance in their administration. They also touch upon lifestyle modifications and nutritional supplements for managing conditions like diabetic neuropathy and CIDP. Dr. Mian highlights the importance of a multifocal approach to pain management and offers insights from his book, “Getting to Pain Free: How to Make Your Body Stop Hurting So That You Can Start Living Again Without Drugs Or Surgery.”

Exploring Regenerative Agriculture and Advanced Nutraceuticals with Nébil Bourguiba, the Vegetal Sourcing Manager for Groupe Berkem, a French company focusing on innovative, plant-based solutions for the nutraceutical, cosmetic, and construction industries. The conversation delves into the issues surrounding industrial chemicals, the importance of regenerative agriculture, and ethical sourcing. Bourguiba discusses the scientific approach his company takes to develop high-quality, organic nutraceutical ingredients and cosmetic products. They also explore the potential of plant-based materials in creating sustainable construction products and the challenges posed by current European regulations. Tune in to learn more about how regenerative practices can lead to healthier, more sustainable products across various industries.

Intelligent Medicine Radio for July 12, Part 1: Carbo-Loading

The profitable conveyor belt of osteoporosis—from bone density screening to powerful medications; Study reveals heart hazards of new bone-building drugs; Carbo-loading before endurance events—are we overdoing it? Barbie gets a CGM; Swallowable sensor in a pill reveals secrets of gut health; Dr. Jeffrey Bland introduces Himalayan Tartary Buckwheat as a hedge against age-related immune decline. 

Intelligent Medicine Radio for July 12, Part 2: Smartphone “Fast”

New study shows mood, attention, brain function improvements after 2-week smartphone “fast”; Natural ways to combat the pain of neuropathy; Solutions for painful swollen lower extremities; Omega-3 reduces depression in bipolar disease; Berberine for blood sugar control; Study demonstrates comprehensive lifestyle program reverses cognitive decline; NSAIDs for knee pain—more is not better; Nighttime pistachio snack curbs pre-diabetes.

References & Resources

Powerful pill can reveal what’s going on in your gut, thanks to miniature sensors
Nat Biotechnol 36, 596 (2018)

Barbie introduces 1st doll with Type 1 diabetes
By Yi-Jin Yu, Good morning America, July 8, 2025

Some bone density treatments linked to increased likelihood of heart attack and atrial fibrillation
Epicresearch.org  June 26, 2025

Strategic carbohydrate feeding improves performance in ketogenic-trained athletes
Clinical Nutrition Volume 51, August 2025, Pages 212-221

Can berberine supplements help manage diabetes
By Marsha Mculloch, MS, RD and Tom Rush, Healthline, February 24, 2025

Nighttime pistachio snacking may reshape gut microbiome in prediabetic adults
Current Developments in Nutrition, Volume 9, Issue 7, 107481

Is your brain aging faster than you? New science offers clues
By Alex Janin, WSJ June 29, 2025

Omega-3s reduce depression and improve brain health in new RCT
GrassRoots Health Nutrient Research Institute  July 9, 2025

Blocking mobile internet on smartphones improves sustained attention, mental health, and subjective well-being
PNAS Nexus. 2025 Feb 18;4(2):pgaf017. doi: 10.1093/pnasnexus/pgaf017

Identifying clinically relevant subgroups of patients with knee pain flares for ibuprofen treatment
Clin Rheumatol. 2025 Jun 25. doi: 10.1007/s10067-025-07539-0. Epub ahead of print.

Palmitoylethanolamide in the treatment of chronic pain: A systematic review and meta-analysis of double-blind randomized controlled trials
Nutrients. 2023 Mar 10;15(6):1350. doi: 10.3390/nu15061350

Q&A with Leyla, Part 1: Red Light Therapy v. Morning Sunlight

• More and more patients are looking for root causes to their ailments
• I’m 51 years old and my PSA is starting to climb. Is there anything I can do to slow the progression?
• Do I really need a red light therapy device or does early morning sunlight provide the same benefit?
• What do you think of the R.E.M.S scan for bone density?

Q&A with Leyla, Part 2: A Weedkiller Worse Than Glyphosate

• A story about Familial Hypercholesterolemia
• The importance of coronary artery calcium scoring in determining the need for a statin
• A weedkiller worse than glyphosate being used in the US
• Can I eat one meal a day indefinitely?