Ask Leyla: What’s the difference between common inflammatory markers?
Q: My husband’s high sensitivity C-reactive protein (hs-CRP) is 1.62 and his homocysteine is 13.1. If they both measure inflammation, why is one result normal and the other one high?
A: While both hs-CRP and homocysteine are markers of inflammation, they are not related.
A high homocysteine represents a glitch in the metabolism of methionine, an amino acid. The conversion of homocysteine back to methionine requires ample amounts of B vitamins such as B6, B12, and folate as well as betaine and trimethylglycine to aid in lowering it. High homocysteine is a risk factor for cardiovascular disease, stroke, Alzheimer’s disease and bone fracture.
Those with the MTHFR polymorphism (a gene mutation) may have high homocysteine levels, although that is not always the case. Nevertheless, it’s an easy fix for most individuals by supplementing with methylated B vitamins such as those found in Methyl Guard Plus. Optimally, we like to see homocysteine levels below 8.
It’s critical to note there are no symptoms of high homocysteine. Only a blood test can reveal if levels are out of range. Because it’s an important risk factor to monitor, ask your doctor for this test since it’s still not yet routinely ordered.
C-reactive protein is a general marker of inflammation in the body but hs-CRP targets inflammation in blood vessels, especially coronary arteries. An hs-CRP reading of 1.62 represents average risk. You can read about targeted therapies to lower CRP here.
To your health!
As you may know, I’ve been doing a weekly “Q&A with Leyla” podcast feature with Dr. Hoffman. Now you can get my perspective and expertise every Friday on my own episode of the Intelligent Medicine Podcast. If you missed last week’s, you can listen here. To be sure you don’t miss out on any of my important insights and information, subscribe today!
2,052 total views, 7 views today
Though we think of declining estrogen as the hallmark of menopause, it's actually common for…
Up to 12 percent of Americans have ulcers at some point in life. Peptic ulcers…
Gallbladder disease is a modern illness. An estimated 20 million Americans have gallbladder disease. The…
I first became cognizant of the vast potential of concentrated nutraceuticals derived from plants known…
Q: I know that too much sugar in my diet is a bad idea, but I…
The recent collapse of the Trump-Ryan healthcare bill in Congress has left an expectant nation…
Hoffman Center Nutritionist Leyla Muedin has a biting response to a recent New York Times…
PhytoGuard taps the benefits of phyto-(plant) nutrients now associated with prevention of degenerative conditions, cancer and heart disease.
PhytoGuard is richly endowed with a high potency extract of green tea, whose polyphenols are now extensively researched for their cancer-blocking potential. Indoles from broccoli extract have specific chemopreventive activity. Curcumin has a broad range of applications in cancer prevention and modulation of inflammatory disorders. Quercetin supplies biflavonoid activity. Tomato-derived lycopene completes PhytoGuard's rich roster of protective nutrients.